Pfizer's 'Knock Out' Still 2025's Most Likeable Ad So Far

Pfizer's 'Knock Out' Still 2025's Most Likeable Ad So Far

The year's most likeable TV ads primarily tugged on heartstrings, according to new first-half data from iSpot. Even months after the Big Game, two of the three most likeable spots (by creative assessment results) were Super Bowl spots: Pfizer's "Knock Out" and Rocket Mortgage's "Own the Dream."

  • Pfizer's spot, showing a child returning home after beating cancer, scored as inspiring with audiences, and achieved brand recognition 9% higher than the pharma norm.
  • Across the 10 most likeable spots from the year's first half, they were spread among a variety of different industries: Pharma, greeting cards, mortgage services, apparel, automotive, investment services and more.
  • Notably, No. 4 and No. 5 (Bombas and Subaru, respectively) both featured a philanthropic component as well, aimed at children.

Check out iSpot's full H1 report here to learn about the most likeable ads, what drove retail foot traffic, and more.